義大利Rizzoli生物力學實驗室，於2011年對114位膝蓋退化患者做PRP注射臨床，

經由結果證實PRP注射後，可減輕關節疼痛、改進關節功能，注射後一般可維持9個月以上。

Platelet-rich Plasma :intra-articular knee injections produced favorable results on degenerative cartilage lesions. 

Knee Surg Sports Traumatol Arthrosc 2010;18(4):472-479

 

注射富含血小板血漿PRP也可以藉由刺激關節膜細胞分泌玻尿酸，進而保持關節腔內的平衡，應是值得期待的治療方式。

Platelet-released growth factors enhance the secretion of hyaluronic acid and induce hepatocyte growth factor production

by synovial fibroblasts from arthritic patients. Rheumatology(Oxford).2007 Oct 17

 

PRP治療顯示對於退化性關節炎的疼痛與症狀緩解，有明顯改善。

Injection of Platelet-rich Plasma in patients with primary and secondary knee osteoarthritis:

A pilot study. Am J Phys Med Rehabil 2010:89:961-969.

 

在疼痛症狀緩解與恢復關節功能比較上，自體PRP注射比玻尿酸注射顯示更好且更長效的治療效果。

Platelet-rich Plasma intra-articular injection versus hyaluronic and viscosupplementation as treatments for cartilage pathology

:from early degeneration to osteoarthritis. Arthroscopy 27(11):1490-1501.

 

PRP注射可減緩關節疼痛、促進關節功能恢復並大大改善病患生活品質。

Autologous platelet gel for tissue regeneration in degenerative disorders of the knee, Blood Transfus,2011 Oct 25:1-6

 

PRP可促進人類肌腱細胞的創傷後再生癒合作用。

“Can Platelet-rich Plasma Enhance Tendon Repair? A Cell Culture Study”Am Sports Med March 7,2008

 

受損肌腱授受PRP增生注射後，可促進肌腱幹細胞分化為成熟肌腱細胞。

Am J Sports Med. 2010 Dec;38(12):2477-86. Epub 2010 Aug 27.

Platelet-rich plasma releasate promotes differentiation of tendon stem cells into active tenocytes.

 

PRP注射外踝部，可成功治療第三度踝關節扭傷。

Conservative treatment using plasma rich in growth factors (PRGF)for injury to the ligamentous complex of the ankle.

Acta Chir Orthop Traumatol Cech.2008 Feb;75(1):28-33

 

血小板生長因子可促進關節膜細胞分泌玻尿酸。

Platelet-released growth factors enhance the secretion of hyaluronic acid and

induce hepatocyte growth factor production by synovial fibroblasts from arthritic patients. Rheumatology(Oxford).2007 Oct 17

 

以PRP增生注射治療網球肘：比打類固醇好!

Am J Sports Med. 2010Feb;38(2);255-62. Positive effect of an autologous platelet concentrate in lateral epicondylitis

in a double-blind randomized trial: platelet-rich plasma versus corticosteroid injection with platelet-follow-up.

 

PRP注射修補非著骨性阿基里腱病變。

Int J Sports Med.2010 Aug;31(8);577-83.Treatment of Achilles tendinopathy with platelet-rich plasma.

 

富含血小板血漿〈PRP〉不僅刺激關節軟組織再生，還有抑制發炎的功效。

Molecular basis of anti-inflammatory action of platelet-rich plasma on human chondrocytes:

mechanisms of NF-K B inhibition via HGF. J Cell Physiol.2010 Nov;225(3):757-66.