Comprehensive hormone supplementation may prevent and improve sarcopnia.
Hormones are found to be very important to work on muscle mass maintenance. Testosterone can be the core hormone on the protein synthesis. Growth hormone and IGF-1 are also associated with the muscle function. Less thyroid hormone can result in less muscle fibrils. Insulin deficiency or insulin resistance may cause the gluconeogenesis in liver and reduce the glucose metabolism in skeletal muscle. Insulin promotes protein anabolism and insulin resistance causes protein catabolism. Comprehensive hormone supplementation may prevent and improve sarcopenia.